INTRA-ABDOMINAL INFECTION
Clinical conditions Pathogen(s) Antibiotic(s) Comments
Peritonitis or diverticulitis

Coliforms
Bacteroides spp
Anaerobic cocci

 IV Amoxicillin + Metronidazole + Gentamicin Step down to cotrimoxazole + metronidazole or in line with cultures.
CAPD-associated peritonitis Staph. epidermidis
Staph. aureus
Coliforms
Pseudomonas		 Vancomycin + ceftazidime Intraperitoneal administration.
Refer to renal unit policy.
Cholecystitis/acute cholangitis Coliforms
Anaerobes
Enterococci		 IV Amoxicillin + Metronidazole + Gentamicin Step down to cotrimoxazole + metronidazole in line with cultures.
Liver abscess Coliforms
Anaerobes
Enterococci
Staph. aureus		 Co-amoxiclav + metronidazole Consider amoebic abscess.

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