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13.12
Hyperhidrosis
Hyperhidrosis is excessive sweating. It can be localised or affect the whole body. Refer to the Department of Dermatology Hyperhidrosis Guideline for further background information and management. The following medicines may be used in the treatment of hyperhidrosis (refer to guideline for place in therapy in relation to severity):
Topical treatments
FIRST CHOICE: ALUMINIUM ANTIPERSPERANTS (Anhydrol Forte®, Driclor®)
Aluminium antiperspirants - Anhydrol Forte®, Driclor®
Aluminium chloride hexahydrate 10% in 4% salicylic gel [unlicensed]
Aluminium
chloride hexahydrate 20% in 4% salicylic gel
[unlicensed]
Glycopyrrolate 2%
in Unguentum M®,
100g [unlicensed]
Glycopyrrolate 2%
in Aqueous Solution,
100ml [unlicensed]
In more severe cases
specialists use iontophoretic treatment for hyperhidrosis of plantar and palmar
areas. Tap water or
Glycopyrronium bromide 0.05%
solution [unlicensed] may be
used as the iontophoresis solution.
Systemic treatments
Systemic treatments for hyperhidrosis
include oral medicines: the anticholinergics:
oxybutynin
[unlicensed use ‘off-label’] and
propiverine
hydrochloride [unlicensed use
‘off-label’]; the beta-blocker:
propranolol
[unlicensed use ‘off-label’] or an SSRI such as
fluoxetine
[unlicensed use ‘off-label’].
Refer to
Hyperhidrosis Guideline for
information on doses used.
Botulinum Toxin Type A (Botox®)
is licensed for use intradermally for severe hyperhidrosis of the axillae
unresponsive to topical antiperspirant or other antihidrotic treatment.
Refer
to the Department of
Dermatology
Hyperhidrosis Guideline
for further information.
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