Dementia Specialist formulary list

**Other indications for particular drugs may be included on completion of further specialist lists**

For information on use of unlicensed medicines or medicines used 'off-label' - click here

The following medicines are approved for prescribing by or on the recommendation of a Psychiatrist or Medicine for the Elderly specialist:

MEDICINE SUMMARY OF RESTRICTED INDICATION CATEGORY PROTOCOL
Clomethiazole capsules Insomnia in the elderly or people with dementia (short-term use).  
Clomethiazole edislate syrup (unlicensed) (available from Movianto as named patient)

Quetiapine tablets

 

Behavioural and psychological symptoms of dementia (BPSD) (Psychosis, aggression, severe agitation/anxiety) in dementia with Lewy bodies (DLB) or in patients with Parkinson’s disease. (unlicensed use ‘off-label’) SEE GOOD PRACTICE GUIDES

Second line for BPSD in AD. (unlicensed use ‘off-label’) SEE GOOD PRACTICE GUIDES

Rationalisation of Antipsychotics in people with Dementia –

Good Practice Guide for initiation of treatment

Good Practice Guide for reduction and cessation of treatment

 

 

Trazodone tablets, capsules, liquid Depressive symptoms and dementia associated agitation. SIGN 86 Management of patients with dementia
Donepezil hydrochloride tablets, orodispersible tablets Mild to moderate Alzheimer’s Disease (AD).

(Note:  in Perth & Kinross)

Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s Disease - Shared Care Agreement (Angus & Dundee). (Staffnet intranet link only).

SIGN 86 Management of patients with dementia

 

 

 

Initial 6 to 9 months memantine prescribed from Psychiatry of Old Age (Angus & Dundee).

Galantamine tablets, m/r capsules, oral solution Mild to moderate AD.
Rivastigmine capsules, oral solution Mild to moderate AD.
Rivastigmine patches Moderately severe AD in patients who require once daily administration or have swallowing difficulties.
Memantine hydrochloride tablets, oral solution Moderate AD in those who are intolerant of or have a contraindication to cholinesterase inhibitors, or those with severe AD.
Galantamine tablets, m/r capsules, oral solution Cognitive decline in people with mixed dementias (unlicensed use ‘off-label’).

(Note:  in Perth & Kinross)

SIGN 86 Management of patients with dementia
Rivastigmine capsules, patches, oral solution Cognitive decline or the management of associated symptoms (behavioural and psychological symptoms (BPSD)) in people with dementia with Lewy bodies (unlicensed use ‘off-label’)

 

Traffic light status information
 To be prescribed by Hospital Specialists Only.
 Can be prescribed in General Practice under the direction of a Specialist.

The following medicines that may be prescribed by specialists in patients with dementia may also be initiated by GPs or non-specialists where appropriate (advice would normally be sought from specialists). These medicines are included here for information and are also within the formulary.

TAF
SECTION
MEDICINE SUMMARY OF RESTRICTED INDICATION PROTOCOL
04.01 Lorazepam tablets Agitation/anxiety in dementia.  
Zopiclone tablets Insomnia in dementia.  
Temazepam tablets, oral solution Insomnia in dementia.  
04.02.01 Risperidone tablets, orodispersible tablets, liquid ▼

Short-term (up to 6 weeks) treatment of persistent aggression in Alzheimer’s Disease (AD) unresponsive to non-pharmacological approaches and when risk of harm to self or others. SEE GOOD PRACTICE GUIDES

Psychosis or severe agitation/anxiety in AD (unlicensed use ‘off-label’). SEE GOOD PRACTICE GUIDES

SIGN 86 Management of patients with dementia

Rationalisation of Antipsychotics in people with Dementia –

Good Practice Guide for initiation of treatment

Good Practice Guide for reduction and cessation of treatment

Haloperidol tablets, oral liquid

Agitation and restlessness in the elderly. SEE GOOD PRACTICE GUIDES

Psychosis or aggression in AD. (unlicensed use ‘off-label’) SEE GOOD PRACTICE GUIDES

04.03 Fluoxetine capsules, liquid Co-morbid depression in dementia. First line choice. SIGN 86 Management of patients with dementia
Mirtazapine tablets, orodispersible tablets Co-morbid depression in dementia. Second line choice.

A Dementia Integrated Care Pathway (ICP) for use in NHS Tayside has been developed. This is not yet available electronically.

Other NHS Tayside guidance that healthcare professionals should be aware of for the care of older adults includes The Management of Delirium in adult and older in-patients and Medication review in frail older people on multiple medicines.

Dementia, delirium and depression are the three most prevalent psychiatric disorders in older people. All three conditions can have similar symptoms and older people may often be suffering from more than one of these conditions making diagnosis difficult. Delirium is very common and often treatable in older people, especially in those in hospital or residential care and despite the fact that delirium is a common and serious condition it is frequently unrecognised. See the NHS Tayside guidance on the management of delirium in adult and older in-patients for information on distinguishing features of delirium, depression and dementia.

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