Dementia Specialist formulary list
**Other indications for particular drugs may be included on completion of further specialist lists**
The following medicines are approved for prescribing by or on the recommendation of a Psychiatrist or Medicine for the Elderly specialist:
MEDICINE | SUMMARY OF RESTRICTED INDICATION | CATEGORY | PROTOCOL |
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Clomethiazole edislate syrup (unlicensed) (available from Movianto as named patient) | |||
Quetiapine tablets
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Behavioural and psychological
symptoms of dementia (BPSD) (Psychosis, aggression, severe
agitation/anxiety) in dementia with Lewy bodies (DLB) or in patients with
Parkinson’s disease. (unlicensed use ‘off-label’) SEE GOOD PRACTICE
GUIDES
Second line for BPSD in AD. (unlicensed use ‘off-label’) SEE GOOD PRACTICE GUIDES |
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Rationalisation of Antipsychotics in people with Dementia –
Good Practice Guide for reduction and cessation of treatment
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Trazodone tablets, capsules, liquid | Depressive symptoms and dementia associated agitation. |
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SIGN 86 Management of patients with dementia |
Donepezil hydrochloride tablets, orodispersible tablets | Mild to moderate Alzheimer’s Disease (AD). |
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Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s Disease - Shared Care Agreement (Angus & Dundee). (Staffnet intranet link only). SIGN 86 Management of patients with dementia
Initial 6 to 9 months memantine prescribed from Psychiatry of Old Age (Angus & Dundee). |
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Traffic light status information | |
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To be prescribed by Hospital Specialists Only. |
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Can be prescribed in General Practice under the direction of a Specialist. |
The following medicines that may be prescribed by specialists in patients with dementia may also be initiated by GPs or non-specialists where appropriate (advice would normally be sought from specialists). These medicines are included here for information and are also within the formulary.
TAF SECTION |
MEDICINE | SUMMARY OF RESTRICTED INDICATION | PROTOCOL |
04.01 |
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Zopiclone tablets | Insomnia in dementia. | ||
Temazepam tablets, oral solution | Insomnia in dementia. | ||
04.02.01 | Risperidone tablets, orodispersible tablets, liquid ▼ |
Short-term (up to 6 weeks) treatment of persistent aggression in Alzheimer’s Disease (AD) unresponsive to non-pharmacological approaches and when risk of harm to self or others. SEE GOOD PRACTICE GUIDES Psychosis or severe agitation/anxiety in AD (unlicensed use ‘off-label’). SEE GOOD PRACTICE GUIDES |
SIGN 86 Management of patients with dementia Rationalisation of Antipsychotics in people with Dementia –
Good Practice Guide for reduction and cessation of treatment |
Haloperidol tablets, oral liquid |
Agitation and restlessness in the elderly. SEE GOOD PRACTICE GUIDES Psychosis or aggression in AD. (unlicensed use ‘off-label’) SEE GOOD PRACTICE GUIDES |
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04.03 | Fluoxetine capsules, liquid | Co-morbid depression in dementia. First line choice. | SIGN 86 Management of patients with dementia |
Mirtazapine tablets, orodispersible tablets | Co-morbid depression in dementia. Second line choice. |
A Dementia Integrated Care Pathway (ICP) for use in NHS Tayside has been developed. This is not yet available electronically.
Other NHS Tayside guidance that healthcare professionals should be aware of for the care of older adults includes The Management of Delirium in adult and older in-patients and Medication review in frail older people on multiple medicines.
Dementia, delirium and depression are the three most prevalent psychiatric disorders in older people. All three conditions can have similar symptoms and older people may often be suffering from more than one of these conditions making diagnosis difficult. Delirium is very common and often treatable in older people, especially in those in hospital or residential care and despite the fact that delirium is a common and serious condition it is frequently unrecognised. See the NHS Tayside guidance on the management of delirium in adult and older in-patients for information on distinguishing features of delirium, depression and dementia.
© 2010 NHS Tayside