Medicine for the Elderly Specialist formulary list

**Other indications for particular drugs may be included on completion of further specialist lists**

For information on use of unlicensed medicines or medicines used 'off-label' - click here

The following medicines are approved for prescribing by or on the recommendation of a Medicine for the Elderly specialist (except botulinum toxin type A, human recombinant parathyroid hormone and teriparatide which are only prescribed by particular specialists – see below.) (Medicine for the Elderly specialists refer patients to these other specialists for these medicines):

TAF SECTION MEDICINE SUMMARY OF RESTRICTED INDICATION CATEGORY PROTOCOL
6.3 Fludrocortisone acetate (unlicensed use ‘off-label’) Orthostatic (postural) hypotension only after interventions as per guidance notes.

Link to Orthostatic Hypotension Guidance Notes

See  SIGN 113 Diagnosis and pharmacological management of Parkinson’s disease

6.6 Denosumab subcutaneous injection (Prolia®▼) every 6 months

Postmenopausal osteoporosis.

2nd line option.

Restricted to patients with a bone mineral density (BMD) T-score < -2.5 and > -4.0 for whom oral bisphosphonates are unsuitable due to contraindication, intolerance or inability to comply with administration instructions. See also protocol.

Local protocol

Tayside MFE Osteoporosis Treatment Algorithm

Zoledronic acid annual intravenous infusion (Aclasta®)

2nd line option.

Postmenopausal osteoporosis in women at increased risk of fractures in patients who are unsuitable for or unable to tolerate oral bisphosphonates.

Tayside MFE Osteoporosis Treatment Algorithm
Strontium ranelate oral sachets

3rd line - for patients who cannot be given oral bisphosphonates, denosumab or annual zoledronic acid.

Postmenopausal osteoporosis in women at high risk of fracture, equivalent to age over 75 years with a previous fragility fracture and a T-score of < -2.4.

See local guidance and MHRA advice for further restrictions/contra-indications/cautions.

Tayside MFE Osteoporosis Treatment Algorithm

MHRA Drug Safety Update April 2013

 

Teriparatide (Forsteo®)

Severe postmenopausal osteoporosis. 4th line.
See also protocol.

Local protocol

Teriparatide or Human recombinant parathyroid hormone are only prescribed by secondary care osteoporosis clinicians.

Human recombinant parathyroid hormone (Preotact®)
Calcitonin injection (Miacalcic®) Prevention of acute bone loss due to sudden immobility.  
9.1 Iron sucrose (Venofer®) Treatment of iron deficiency when oral iron preparations are ineffective or cannot be used. First choice parenteral iron preparation.  
Ferric carboxymaltose (Ferinject®▼)

Second choice parenteral iron preparation. Restricted to administration by intravenous infusion.

May be used on advice of Renal specialists or where administration is required as a total dose infusion to ensure full dosage received (e.g. out-patient clinics, in-patients when short expected length of stay).
10.2 Baclofen Relief of spasticity of voluntary muscle associated with neurological damage including stroke. See SIGN 118 Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning.
Tizanidine Treatment of spasticity associated with stroke (unlicensed use ‘off-label’).
Botulinum toxin type A (Botox®) Focal spasticity, including the treatment of wrist and hand disability due to upper limb spasticity associated with stroke in adults.

Only prescribed by and administered by the consultant from the Centre for Brain Injury Rehabilitation

See SIGN 118 Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning

 

 May be prescribed by Hospital Specialists only
 May be prescribed in General Practice under the direction of a Specialist

See the guideline Medication review in frail older people on multiple medicines for further information on prescribing and medication review in older people.

See the guideline The Management of Delirium in Adult and Older In-patients for information on the prevention, diagnosis and management of delirium.

For other Medicine for the Elderly related prescribing and referral guidance see the Medicine for the Elderly Staffnet site and the Clinical Pathways & Information Staffnet website and select ‘Medicine for the Elderly’.

For information on Dementia see the Dementia specialist formulary list and formulary section 4.11.

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