A

New medicine

Indication

Formulary status

DTC
Supplement

Date

Abacavir (Ziagen®)

HIV

HOSPITAL ONLY

50

2005

Abacavir/lamivudine (Kivexa®)

HIV

HOSPITAL ONLY

50

2005

Abatacept (Orencia®) (888/13)

In combination with methotrexate, for the treatment of moderate to severe active rheumatoid arthritis in adult patients who responded inadequately to previous therapy with one or more disease-modifying anti-rheumatic drugs including methotrexate or a TNF-alpha inhibitor.

HOSPITAL ONLY
(4th line agent )

 

129

Aug/Sept 2013
Abatacept (Orencia®) (618/10) Juvenile idiopathic arthritis HOSPITAL ONLY (Paediatric Rheumatology Clinic)

112

96

Dec 2011

Apr/May 2010
Abatacept (Orencia®) (719/11) Moderate to severe active rheumatoid arthritis HOSPITAL ONLY

127
110
72

May 2013
Oct
2011
Sept 2007
Abiraterone (Zytiga®) (873/13) Treatment of adults with previously treated anaplastic lymphoma kinase (ALD)-positive advanced non-small cell lung cancer (NSCLC) Not recommended 127 May 2013

Abiraterone acetate (Zytiga®) (764/12)

 

With prednisone or prednisolone for the treatment of metastatic castration-resistant prostate cancer (mCRPC) in adult men whose disease has progressed on or after a docetaxel-based chemo-
therapy regimen.

HOSPITAL ONLY (Oncology)

 

119
116

Aug/Sept 2012
Apr/May 2012
Aclidinium (Eklira Genuair®) (810/12) COPD Formulary

123
122

Jan 2013
Dec 2012
Adalimumab (Humira®) (880/13) Severe active Crohn's disease (6 to 17 years) HOSPITAL ONLY
(Paediatric Gastroenterology)

129

Aug/Sept 2013
Adalimumab (Humira®) (881/13) Active polyarticular juvenile idiopathic arthritis (2 to 17 years) HOSPITAL ONLY
(Paediatric Rheumatology)

129

Aug/Sept 2013
Adalimumab (Humira®) (858/13) Severe axial spondyloarthritis HOSPITAL ONLY 127 May 2013
Adalimumab (Humira®) (824/12) Moderately active Crohn's disease Not recommended

122

Dec 2012
Adalimumab (Humira®) (800/12) Ulcerative colitis Not recommended

119

Aug/Sept 2012
Adalimumab (Humira®) (738/11) Active polyarticular juvenile idiopathic arthritis in children and adolescents (4-17 years) HOSPITAL ONLY (Paediatric Rheumatology Clinic)

112

Dec 2011
Adalimumab (Humira®) (533/09) Adolescents with active polyarticular juvenile idiopathic arthritis (13-17 years) in combination with methotrexate HOSPITAL ONLY (Paediatric Rheumatology Clinic)

86

Jan 2009
Adalimumab (Humira®)   Chronic plaque psoriasis HOSPITAL ONLY 80 June 2008
Adalimumab (Humira®) (417/07) Severe, active Crohn's disease HOSPITAL ONLY
(GI Clinic)

122
74

Dec 2012
Nov 2007
Adalimumab (Humira®)   Severe active ankylosing spondylitis HOSPITAL ONLY (Rheumatology Clinic) 64 2006

Adalimumab (Humira®)

Rheumatoid arthritis

HOSPITAL ONLY
(Rheumatology Clinic)

34

2003

Adalimumab (Humira®)

Psoriatic arthritis

HOSPITAL ONLY

55

2006

Adapalene (Epiduo®) (682/11) Acne vulgaris Non-formulary - absence of clinician demand

137
104

Apr/May 2014
Mar 2011

Adefovir (Hepsera®)

Chronic Hepatitis B

HOSPITAL ONLY

50
29

2005
2003

Adrenaline tartrate (Jext®) (687/11) Severe acute allergic reactions Formulary

111

Nov 2011
Afatinib (Eylea®) (954/14) For adults for treatment of visual impairment due to macular oedema HOSPITAL ONLY 137 Apr/May 2014
Afatinib (Giotrif®) (920/13)

Adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) with activating EGFR mutation(s)

HOSPITAL ONLY
(Oncology)

136

 

Mar/Apr 2014
Aflibercept (Eylea®) (1003/14) For adults for the treatment of visual impairment due to diabetic macular
oedema (DMO).
SMC restriction: treatment of visual impairment due to DMO in adults with best corrected visual acuity (BCVA) 75 Early Treatment Diabetic Retinopathy Study (ETDRS) letters or less at baseline

Formulary
2nd line choice for DMO in patients unresponsive to ranibizumab treatment
HOSPITAL ONLY

143

Nov/Dec 2014
Aflibercept (Zaltrap®) (878/13) Metastatic colorectal cancer (mCRC) HOSPITAL ONLY
(Oncology)

136
129

Mar/Apr 2014
Aug/Sept 2013
Aflibercept (Eylea®) (954/14) For adults for treatment of visual impairment due to macular oedema HOSPITAL ONLY
2nd line choice
137 Apr/May 2014
Aflibercept (Eylea®) (857/13) Neovascular (wet) age-related macular degeneration Non-formulary - alternatives preferred 127 May 2013
Agomelatine (Valdoxan®) (564/09) Major depressive disorders in adults Not recommended

99 
93

Aug/Sept 2010
Oct/Nov 2009
Alemtuzumab (Lemtrada®) (959/14) RRMS Non-formulary - protocol pending 140 Jul/Aug 2014
Alemtuzumab (MabCampath®) (494/08) B-cell chronic lymphocytic leukaemia (B-LL) HOSPITAL ONLY 82 Aug/Sept 2008

Alendronate/colecalciferol (Fosavance®)

Postmenopausal osteoporosis

Non-formulary

54

 

2005

Alglucosidase alfa (Myozyme®) 9352/07) Pompe disease Not recommended 67 Mar 2007
Aliskiren (Razilex®) (462/08) Essential hypertension Not recommended

114
95

86
79

Feb 2012
Feb/Mar 2010
Jan 2009
May 2008
Alitretinoin (Toctino®) (538/09) Severe chronic hand eczema HOSPITAL ONLY
(Dermatology Clinic)

87

Mar 2009
Alogliptin (Vipodomet®) (998/14)    Adult patients aged 18 years and older with Type 2 diabetes mellitus Non-formulary - absence of clinician demand 142 Oct/Nov 2014

Alogliptin (Vipidia®) (937/14)   

 

Type 2 diabetes mellitus in adults

Non-formulary - absence of clinician demand

141

136
Sept/Oct 2014
Mar/Apr 2014
Alteplase (Actilyse Cathflo®) (714/11) Acute ischaemic stroke HOSPITAL ONLY
(NW Stroke unit/A&E, PRI Gen Med)
Stroke specialist list

118

July 2012

Alteplase (Actilyse Cathflo®)
(717/11)

Thrombolytic treatment of occluded central venous access devices

Non-formulary - absence of clinician demand

113
109

Jan 2012
Sept 2011

Alteplase (Actilyse®) (87/04)

Acute ischaemic stroke

HOSPITAL ONLY

37

 

2004

Ambrisentan (Volibris®) (511/08) Class II and III pulmonary arterial hypertension   84 Nov 2008
Amifampridine (Firdapse®) (660/10) Lambert-Eaton Myasthenic Syndrome (LEMS) in adults Not recommended

119
100

Aug/Sept 2012
Oct/Nov 2010
5-aminolaevulinic acid (Ameluz®) (811/12) Treatment of actinic keratosis of mild to moderate intensity on the face and scalp HOSPITAL ONLY
(Dermatology Clinic)
123 Jan 2013
Amlodipine/valsartan (Exforge®) (350/07) Hypertension Non-formulary 67 Mar 2007

Anagrelide (Xagrid®)

Thrombocythaemia

HOSPITAL ONLY

54
50

2005

Anakinra (Kineret®)

Rheumatoid arthritis

 

 

2002

Anastrozole (Arimidex®)

ER positive early breast cancer

 

63
53
37

2006
2005
2004
 

Anidulafungin (Ecalta®) (465/08) Invasive candidiasis HOSPITAL ONLY 85
84
80
Dec 2008
Nov 2008
June 2008

Apixaban 2.5mg and 5mg film-coated tablets (Eliquis®) (836/13)
 

prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation (NVAF),

Formulary
(Restricted to patients who have poor INR control on warfarin or with allergy to, or incontrollable side effects from coumarin aticoagulants)

125

Mar/Apr 2013
Apixiban (Eliquis®) (741/11) Prevention of VTE Not recommended

113

Jan 2012

Aprepitant (Emend®)

Prevention of cisplatin-induced nausea and vomiting

HOSPITAL ONLY

46

 

2004

Aprepitant (Emend®) (242/06)

Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy

Not recommended

112
56

Dec 2011
2006

Argatroban (Exembol®) (812/12)

Anticoagulation in adult patients with heparin-induced thrombocytopenia type II who require parenteral antithrombotic therapy

HOSPITAL ONLY
(2nd line)

 

129
122

Aug/Sept 2013
Dec 2012
Aripiprazole (Abilify Maintena®) (962/14) Schizophrenia in adults HOSPITAL ONLY
 
138 May/June 2014
Aripiprazole (Abilify®) (891/13) Moderate to severe manic episodes in Bipolar 1 Disorder in adolescents aged 13 years and older HOSPITAL ONLY
Child & Adolescent Mental Health Services (CAMHS)

130

 
Sept/Oct 2013

Aripiprazole (Abilify®) (630/10)

Schizophrenia in adolescents 15 years and older

HOSPITAL ONLY
(Child/adolescent psychiatry)

99 
85
52
43

Aug/Sept 2010
Dec 2008
2005
2004

Aripiprazole (Abilify®) orodispersible tablets Moderate to severe manic episodes in bipolar 1 disorder  

90
82

June 2009
Aug/Sept 2008

Asenapine (Sycrest®) (762/12)

Treatment of moderate to severe manic episodes associated with bipolar I disorder in adults.

Not recommended

116

Apr/May 2012

Atazanavir (Reeyataz®) (656/10)

HIV

HOSPITAL ONLY (HIV Clinic)

101
86
85
45
44

Dec 10/Jan 2011
Jan/Feb 2009
Dec 2008
2004

Atomoxetine (Strattera®) (909/13)

ADHD - adults

Formulary
(GP under direction of Mental Health Specialist)

 

 

143
132
 

Nov/Dec 2014
Nov/Dec 2013
 

Atomoxetine (Strattera®)

ADHD - children of 6 years and older or in adolescents

Specialist treatment pathway - GPs may prescribe under the direction of a specialist in childhood behavioural disorders 52
49
2005
Atorvastatin (Lipitor®) (766/12)

Adjunct to diet for reduction of
elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia or combined  hyperlipidaemia when response to diet and other nonpharmacological measures is inadequate;
Reduction of  total-C and LDL-C in adults with homozygous familial hypercholesterolaemia as an adjunct to other lipid-lowering treatments or if such treatments are unavailable;
Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event, as an adjunct to correction of other risk factors.

GPs may prescribe under the direction of a paediatric tertiary centre

116

Apr/May 2012

Atorvastatin (Lipitor®)

Hypercholesterolaemia in children

 

54

2005

Avanafil (Spedra®) (980/14) Erectile dysfunction in adult men. Not recommended

139

 
June/July 2014
Axitinib (Inlyta®) (855/13) Advanced renal cell carcinoma (RCC) HOSPITAL ONLY
(Oncology)
132
127
Nov/Dec 2013
May 2013
Azacitidine (Vidaza®) (589/09) Adult patients not eligible for haematopoietic SCT with intermediate-2 and high risk MDS, CMML or AML.

Non-formulary - pending
protocol

116
110
96

Apr/May 2012
Oct 2011
Apr/May 2010
Azelaic acid (Finacea® 15% Gel) (359/07) Papulopustular rosacea Non-formulary 68 May 2007
Azelastine hydrochloride (Dymista® nasal spray) (921/13)

For the relief of symptoms of moderate to severe seasonal and perennial allergic rhinitis if monotherapy with either intranasal antihistamine or glucocorticoid is not considered sufficient.

Formulary

144
142
133

Jan/Feb 2015
Oct/Nov 2014
Dec 13/Jan 14
Azilsartan medoxomil (Edarbi®) (803/12) Treatment of essential hypertension in adults Not recommended

119

Aug/Sept 2012
Azithromycin (Zedbac®) (950/14) CAP and PID HOSPITAL ONLY
Under direction of ID or Microbiology
137 Apr/May 2014
Azithromycin dihydrate (Azyter®) (804/12) Conjunctivitis caused by susceptible strains Not recommended

119

Aug/Sept 2012
Aztreonam lysine (Cayston®) (753/12) Suppressive therapy of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with CF aged 18 years and older Not recommended

115

 
Mar/Apr 2012

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