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Use
of Topical Corticosteroids
- Topical
corticosteroid preparations are used in the treatment of inflammatory conditions
of the skin other than those due to an infection. They are not
curative, and should be backed up with other measures, in particular
irritant avoidance and regular emollients.
- Topical steroids should be applied thinly, once or twice daily.
When applying along with an emollient, it doesn’t matter which agent is
applied first, although ideally there should be a 15-30 minute gap between the
two applications.
- They should not be used indiscriminately in pruritus, urticaria, or in
undiagnosed rashes. They are contraindicated in rosacea, and care should be
taken with regular review when treating any facial eruption where the diagnosis
is unclear. Potent steroids should
only be used in psoriasis (other than scalp) under specialist supervision due to
the risk of provoking a severe pustular flare.
Potent steroids can be used in recalcitrant conditions such as
palmoplantar pustulosis, lichen simplex and nodular prurigo, as long as such
patients are reviewed regularly to ensure treatment is appropriate.
- Choice of steroid strength will depend on the nature of the condition
being treated, the age of the patient and the site of disease, the aim being to
use the weakest preparation that will suppress the inflammation.
Particular care should be taken when treating children (especially under
wet wrap dressings), faces and flexures. It
is reasonable to supply two strengths for patients with chronic conditions, one
to be used for maintenance and a stronger one for short-term use during
flare-ups.
- Compound preparations, which usually contain antimicrobial agents, are
useful where there is overt secondary infection. Their use otherwise is
debatable, although they are often used where
there may be a microbial component present such as in flexures. Those that
contain fusidic acid should only be
used for short periods of time (up to 7
days) to reduce the likelihood of developing bacterial resistance.
- Prolonged use of potent steroids will lead to skin atrophy with easy
bruising and striae formation and can suppress the pituitary-adrenal axis.
- Use
on any strength of topical steroid on the face may cause a rosacea-like papular eruption (perioral dermatitis).
- Care
should be taken with topical steroid use around the eyes because of the
possibility of increased ocular pressure and cataract formation. In
general, only mildly potent steroids should be used for as short a time as
possible.
Fingertip
units can
also be helpful when determining prescription quantities. One fingertip unit
(the amount, approximately 0.5g, which covers the distal phalanx of the
forefinger when squeezed out of the tube) is sufficient to cover the area of
both hands in an adult.
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